This stimulating new edition of the well-respected title primarily covers medically important antimicrobial agents, but also includes some compounds not in current medical use, which have been invaluable as research tools in biochemistry. The book's coverage reflects the evolution of molecular biology's impact on our understanding of the mechanisms of antimicrobial action and drug resistance. New material deals with the remarkable recent developments in unraveling the complex molecular details of drug interactions with key targets. The new addition also reviews key advances in the biochemistry and molecular biology of drug-resistant pathogens.
This stimulating new edition of the well-respected title Biochemistry and Molecular Biology of Antimicrobial Drug Action primarily covers medically important antimicrobial agents, but also includes some compounds not in current medical use which have been invaluable as research tools in biochemistry.
Since the previous edition, of this book, the impact of molecular biology on our understanding of the mechanisms of antimicrobial action and drug resistance has evolved significantly. This is reflected in the book's coverage with new material covering the remarkable recent developments in unraveling the complex molecular details of drug interactions with such key targets as ribosomes and the enzymes of nucleic acid replication and microbial cell wall biosynthesis. The new addition also reviews key advances in the biochemistry and molecular biology of drug-resistant pathogens including viruses, parasitic protozoa, fungi and the much feared 'superbugs' such as MRSA.
Completely updated and rewritten, Biochemistry and Molecular Biology of Antimicrobial Drug Action will be of great use to medical and biological sciences students taking courses in pharmacology, molecular biology, microbiology, biochemistry and chemotherapeutics. Because of the wealth of information within the covers of this important book, all those involved in research into drug action and development, whether in the pharmaceutical industry or academia, will find Biochemistry and Molecular Biology of Antimicrobial Drug Action invaluable. It should also be on the shelves of all libraries, in university medical schools and departments of biological sciences, biochemistry and pharmacology.
From the reviews of the sixth edition:
"This sixth edition builds on the successful formula of its predecessors with an accessible small format, clear diagrams and illustrations, key antibiotic structures and an engaging explanatory text. ? the great strength ... is that it has managed to convey the essentials of the topic without ? expanding in girth at each edition. ? this book remains the first port of call for those requiring an overview of the topic or seeking a starting point for more in-depth information on an unfamiliar antimicrobial." (Jonathan H Cove, British Toxicology Society Newsletter, Winter, 2005)
