A valuable reference tool for professionals involved in the industry, Drug Metabolism in Pharmaceuticals covers new tools such as LC-MS and LC-MS-NMR along with experimental aspects of drug metabolism. This work fills a gap in the literature by covering the concepts and applications of pharmaceutical research, development, and assessment from the point of view of drug metabolism. By providing both a solid conceptual understanding of the drug metabolism system, and a well illustrated, detailed demonstration and explanation of cutting edge tools and techniques, this book serves as a valuable reference tool for bench scientists, medical students, and students of general health sciences.
Explains All The Latest Tools And Technologies In Drug Metabolism
Drug Metabolism Handbook is dedicated to helping bench scientists take full advantage of the latest and most advanced tools and techniques in the field of drug metabolism. From creating new molecular entities to drug development to troubleshooting, the book explains the concepts of drug metabolism and guides readers through its applications in pharmaceutical research, development, and assessment.
Concise and easy to follow, Drug Metabolism Handbook offers:
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Succinct reviews of drug metabolism that underscore the importance of the human metabolic system as well as pharmacokinetics and drug interactions
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Thorough and carefully referenced reviews of most drug metabolism phase I and phase II metabolic enzymes
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Illustrative case studies that highlight the critical role of drug metabolism in the drug development process
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Descriptions of the latest findings and tools such as online H-D exchange, LC-ram, LC-MS/MS, and LC-MS-NMR
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Full coverage of recent FDA regulations and guidelines for drug safety
Each chapter is written by one or more leading experts in the field of drug metabolism. Contributions are based on the authors' own first hand experience at the bench as well as a thorough examination of the literature.
By combining a solid conceptual understanding of the drug metabolism system with detailed explanations of the latest cutting-edge tools and techniques, this book is essential readingfor pharmaceutical scientists, students at universities, and all other researchers involved in drug development.
