This open access book analyzes the limitations of top-down intervention programs designed by the state to address the problem of unemployment among marginalized communities in Africa and foregrounds the centrality of IKS in fostering entrepreneurship. Samuel Ojo Oloruntoba, Inocent Moyo, and Lethiwe Zondo examine the solutions to these problems within the ongoing debate on decolonization of knowledge and epistemic justice. The contributors argue that when the voices of the marginalized communities are taken into consideration in the design of employment and entrepreneurship policies, such policies would be more effective, affirming the agency and rights within these communities. Using case studies and theoretical research, this book investigates how a better engagement with marginalized communities and indigenous knowledges in the design of entrepreneurship and employment policies could foster more positive outcomes in Africa. This book recenters the voices of Indigenous youth within entrepreneurship programs to highlight the interests, priorities, and challenges of these communities. This edited volume was produced in the context of the African Indigenous Knowledge Research Network (AIKRN) in partnership with the Mastercard Foundation. This was a two-year initiative that ran between 2023 and 2025 to uncover and promote sustainable and scalable opportunities for youth employment grounded in Indigenous African knowledge systems and values. The views expressed do not necessarily represent those of the Mastercard Foundation, its staff, or its Board of Directors. The ebook editions of this book are available open access under a CC BY-NC-ND 4.0 licence on bloomsburycollections.com. Open access provided in partnership with the Mastercard Foundation.