Saranya Wyles, M.D., Ph.D.,is an Associate Professor of Dermatology and Regenerative Medicine at Mayo Clinic. As a dermatologist-scientist, she specializes in skin health, regenerative medicine and healthy skin aging. Dr. Wyles coined the term skinspan to describe the length of time skin remains healthy, resilient, functional, and capable of repair across the human lifespan. At the Mayo Clinic Center for Aesthetic Medicine and Surgery, her clinical approach combines evidence-based skincare with advanced techniques to prevent and treat the visible and underlying effects of aging.

In addition to her clinical work, Dr. Wyles directs the Regenerative Dermatology and Skin Longevity Laboratory, where she leads research focused on skin aging, wound healing, cellular senescence, and tissue regeneration. Her work examines how age-related cellular changes contribute to declines in skin function and regeneration, and how emerging regenerative approaches, including peptide-based and biologically active therapies, may restore skin resilience and healing capacity. This research informs the development of next-generation dermatologic treatments aimed at improving outcomes for people with age-related, and difficult-to-heal skin concerns. Dr. Wyles also developed a pioneering curriculum in regenerative medicine to train future physicians in innovative approaches to dermatology and skin health.

Dawn Davis, M.D.,is a Professor of Dermatology and Pediatrics at Mayo Clinic. A pediatrician and dermatologist, she aims to help all people feel comfortable, confident and empowered in their skin. She specializes in inflammatory and complex skin diseases, including eczema (atopic dermatitis), psoriasis and neurovascular disorders. Dr. Davis also has specific expertise in skin health in children and during pregnancy, with a focus on safe, effective, and individualized care.

She collaborates with multidisciplinary teams of nationally and internationally recognized experts in pediatrics, dermatology, allergy, vascular medicine, neurology, anesthesiology and psychiatry. Together, their work focuses on helping patients manage complex dermatologic conditions, improve skin health and enhance quality of life.

Dr. Davis's research centers on understanding the underlying mechanisms of skin disease and the connection between skin health and overall health. Her work includes studying genetic and individualized factors that influence skin function and healing, evaluating the effectiveness of dermatologic treatments, and examining how skin disease affects quality of life and long-term health.

Dr. Wyles and Dr. Davis both live in Rochester, Minnesota.