This edited collection investigates how Deleuze's interventions into cosmological thinking have transformed, challenged, or influenced, as well as been influenced by, the ways that cosmology has been thought and determined from the perspective of the philosophic tradition as well as from the perspective of science and arts.These sixteen essays apply Deleuze's cosmological perspective to a range of scientific, metaphysical, philosophical, and aesthetic issues, illustrating the intertwinement of the various modes of thought (philosophy, science and arts) on a cosmic scale, which lead to new ways of understanding relational beings, time/space, processes of variation, folding, potentiality and creativity. By integrating the observations and speculations of quantum theory, as well as other areas of cosmological thinking, with Deleuze's cosmological vision, we find that philosophy, sciences and arts can provide each other with mutual inspiration, pushing the boundaries of thought to the outer reaches of the known and beyond.