The cotton crop is eminently tropical and is grown in most warm climate regions, with the world's largest producers being China, the USA, India and Brazil, among others. Despite being a relatively drought-resistant crop, its yield can be significantly reduced when severe soil water deficits are established. The cotton plant's water consumption during its cycle varies depending on the cultivar, cultural practices, soil moisture availability and atmospheric demand. Mineral fertilization is a recognized factor of great importance in agricultural production, and of the mineral nutrients supplied through chemical fertilization, nitrogen receives the most attention. Water reuse in irrigation is a viable alternative in areas where water is scarce and plants can benefit from the materials dissolved in effluents, such as organic matter, nitrogen, phosphorus, potassium and micronutrients. Considering these aspects, the book describes the effects of different levels of wastewater available in the soil and different doses of nitrogen on the cotton crop, cultivar BRS 200 Marrom.